Vitamin B12 vs Biotin

Evidence-based comparison of Vitamin B12 and Biotin — absorption, dosage, safety, and which is best for your needs.

Reviewed by: Supplement Hub Editorial Team · Category: Vitamin · Updated:

Vitamin B12

Mitochondrial support: Enhances mitochondrial efficiency and biogenesis; Serotonin modulation: Influences serotonin synt

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Biotin

Hair support: Supports hair follicle growth and nutrient delivery

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Detailed Comparison

	Vitamin B12	Biotin
Category	Vitamin	Vitamin
Mechanism	Mitochondrial support: Enhances mitochondrial efficiency and biogenesis; Serotonin modulation: Influences serotonin synt	Hair support: Supports hair follicle growth and nutrient delivery
Safety	Vitamin B12 has not been shown to cause any harm, even at high doses.	Biotin has not been shown to cause any harm. However, supplements that contain biotin above recommended amounts may cause false results in some lab te

Which Should You Choose?

Vitamin B12 may be better if: Maruvada P, Stover PJ, Mason JB, Bailey RL, Davis CD, Field MS, et al. Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: A summary, and perspectives, fro

Biotin may be better if: Hair support: Supports hair follicle growth and nutrient delivery