Vitamin B6 vs Vitamin B12
Evidence-based comparison of Vitamin B6 and Vitamin B12 — absorption, dosage, safety, and which is best for your needs.
Vitamin B6
Mitochondrial support: Enhances mitochondrial efficiency and biogenesis; Serotonin modulation: Influences serotonin synt
Full GuideVitamin B12
Mitochondrial support: Enhances mitochondrial efficiency and biogenesis; Serotonin modulation: Influences serotonin synt
Full GuideDetailed Comparison
| Vitamin B6 | Vitamin B12 | |
|---|---|---|
| Category | Vitamin | Vitamin |
| Mechanism | Mitochondrial support: Enhances mitochondrial efficiency and biogenesis; Serotonin modulation: Influences serotonin synt | Mitochondrial support: Enhances mitochondrial efficiency and biogenesis; Serotonin modulation: Influences serotonin synt |
| Safety | People almost never get too much vitamin B6 from food or beverages. However, taking high amounts of vitamin B6 from supplements for a year or longer c | Vitamin B12 has not been shown to cause any harm, even at high doses. |
Which Should You Choose?
Vitamin B6 may be better if: Prospective studies on vitamin B6 supplements to treat morning sickness have had mixed results. In two randomized, placebo-controlled trials, 30–75 mg of oral pyridoxine per day significantly decrease
Vitamin B12 may be better if: Maruvada P, Stover PJ, Mason JB, Bailey RL, Davis CD, Field MS, et al. Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: A summary, and perspectives, fro