Iodine Dosage Guide

Recommended daily intake by age and gender — based on NIH Dietary Reference Intakes.

Our assessment

Based on the data, iodine is essential for health, but the margin between adequate intake and excess is narrow. The most important safety finding is that getting too much iodine can cause the same symptoms as deficiency, including goiter (an enlarged thyroid gland), as well as thyroid gland inflammation and thyroid cancer NIH ODS ↗. This paradoxical effect requires careful monitoring.

Safety profile

Specific side effects from high iodine intake include: burning of the mouth, throat, and stomach; fever; stomach pain; nausea; vomiting; diarrhea; weak pulse; and coma NIH ODS ↗. These effects are associated with very large doses (several grams). Data on the exact number of adverse event reports from the FDA data provided is not available; the provided data does not include FDA report counts FDA FAERS ↗.

How it works

Iodine is a critical component of thyroid hormones, which regulate metabolism, growth, and development NIH ODS ↗. The data indicates that both deficiency and excess iodine can disrupt thyroid function, leading to conditions like goiter and thyroid inflammation NIH ODS ↗.

Our recommendation

Be cautious with supplementation. The daily upper limits for iodine include intakes from all sources NIH ODS ↗. Those taking antithyroid medications such as methimazole (Tapazole) should be especially cautious, as high doses of iodine with these medications could cause interactions NIH ODS ↗. If you have a thyroid condition or are on thyroid medication, consult a healthcare provider before taking iodine supplements NIH ODS ↗.

AI-assisted analysis. Data sourced from NIH ODS.

Understanding RDAs

Dietary Reference Intakes (DRIs) are a set of reference values used to plan and assess nutrient intakes of healthy people. They include:

  • RDA (Recommended Dietary Allowance) — The average daily intake sufficient to meet the nutrient requirements of nearly all (97-98%) healthy individuals.
  • AI (Adequate Intake) — Established when evidence is insufficient to develop an RDA. Based on observed nutrient intake by healthy people.
  • UL (Tolerable Upper Intake Level) — The maximum daily intake unlikely to cause adverse health effects. Exceeding the UL increases the risk of toxicity.

Values vary by age, gender, and life stage (pregnancy, lactation).

Source: National Academies of Sciences, Engineering, and Medicine

Recommended Dietary Allowance

Iodine RDA / AI by Age and Gender
Life StageRecommended Amount
Birth to 6 months110 mcg
Infants 7–12 months130 mcg
Children 1–8 years90 mcg
Children 9–13 years120 mcg
Teens 14–18 years150 mcg
Adults150 mcg
Pregnant teens and women220 mcg
Breastfeeding teens and women290 mcg

Source: National Academies of Sciences, Engineering, and Medicine