Interaction Warning

Calcium & levothyroxine

Our assessment

Based on the provided data, levothyroxine is a synthetic thyroid hormone used to treat hypothyroidism. The overall safety profile is well-established, but precise risk quantification requires specific FDA adverse event report counts. Data not available for overall report volume.

How it works

Levothyroxine replaces or supplements the body's natural thyroid hormone, which is critical for metabolism, heart function, and brain development. By restoring normal hormone levels, it helps regulate energy, weight, and mood. Data not available for mechanism details beyond general function.

Safety profile

Based on FDA data, specific side effect reports with counts are not provided in the data section. Common side effects from general medical knowledge are not permitted here. Data not available for side effect report counts. No drug interaction data was provided for this supplement.

Our recommendation

This analysis is limited by the data provided. For a complete safety profile, you should consult the prescribing information and FDA data directly. Data not available for specific populations, dose thresholds, or interaction cautions. Always take levothyroxine as prescribed by your healthcare provider FDA FAERS ↗.

AI-assisted analysis. Data sourced from NIH ODS.

MODERATE INTERACTION

Calcium may interact with levothyroxine. Calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin. Calcium supplements may also reduce the absorption of iron and zinc. Proton pump inhibitors, loop diuretics, and corticosteroids can decrease calcium absorption.

Safe Alternatives

These supplements have no known interaction with levothyroxine:

More Supplement-Drug Interactions

Browse all supplement-drug interactions