GNC Calcium Citrate Plus
Brand: GNC · Form: SUPPLEMENT FORM, OTHER [E0172]
Our assessment
The evidence shows that calcium is essential for bone health, but the specific product you are asking about, GNC Calcium Citrate Plus, has data available only for its main ingredient. Our assessment: calcium citrate is a well-absorbed form of calcium, which can be a good option for you if you take it on an empty stomach or have digestive concerns. However, the data also reveals important safety considerations you need to know before starting this supplement [NIH ODS].
How it works
Think of calcium as a master mineral for your body. It works through two primary mechanisms: bone mineralization, where it supports bone density and mineral deposition, and neuromuscular relaxation, where it supports muscle relaxation and nerve signaling [NIH ODS]. This means calcium plays a direct role in keeping your bones strong and your muscles and nerves functioning properly.
Safety profile
Safety data for this supplement is based on the ingredient calcium. The FDA has received 592,059 total adverse event reports across all supplements, though this number is not specific to this product alone [FDA data]. The risks are significant: some research suggests that high calcium intakes might increase the risk of heart disease and prostate cancer. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. You should also be aware that calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Our recommendation: Do not start this supplement without first consulting your doctor, especially if you take any prescription medications. Because of the serious potential side effects, including heart and kidney risks, a healthcare provider can help you determine if a calcium supplement is right for you and at what dose. If you do use it, take calcium citrate separately from the medications listed above to avoid absorption issues [NIH ODS] [FDA data].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | GNC |
|---|---|
| Serving Size | |
| Contents | 180.0 Caplet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide