Physician's Preference Active Folate Methylfolate
Brand: Physician's Preference · Form: CAPSULE [E0159]
Our assessment
Our assessment: The evidence shows that Physician's Preference Active Folate Methylfolate contains calcium, a mineral essential for your body. However, we must be clear about what the data supports. Calcium is a key player in bone mineralization, helping to support bone density and mineral deposition, and it also plays a role in neuromuscular relaxation and nerve signaling [NIH ODS]. The data does not provide specific information on the methylfolate component itself, so our analysis focuses on the calcium content.
How it works
Think of calcium as a structural building block for your bones and a signaling molecule for your nerves and muscles. It works by supporting bone density and mineral deposition, which helps keep your skeleton strong. At the same time, it facilitates neuromuscular relaxation, allowing your muscles to relax properly after contracting and supporting healthy nerve signaling throughout your body [NIH ODS].
Safety profile
Safety profile: Data not available for this specific product's adverse events. The FDA has received a total of 592,059 adverse event reports across all supplements, but specific numbers for this product are not provided. For the calcium ingredient, some research suggests that high calcium intakes might increase the risk of heart disease and prostate cancer. High levels of calcium in your blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Additionally, calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Our recommendation: Because the data on the specific methylfolate component is not available, we cannot provide a confident recommendation for this product as a whole. If you are considering this supplement for its calcium content, be aware of the potential risks from high intakes and the medication interactions listed. Always consult your healthcare provider before starting any new supplement, especially if you take prescription medications. For general calcium needs, food sources are often preferred, and you should discuss your specific health goals with your pharmacist or doctor.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Physician's Preference |
|---|---|
| Serving Size | |
| Contents | 120.0 Vegetarian Capsule(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide