21st Century Papaya Enzyme
Brand: 21st Century · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that 21st Century Papaya Enzyme is a digestive supplement, but the only ingredient with detailed data provided is calcium. The primary benefit of the calcium in this product is to support bone mineralization and neuromuscular relaxation [NIH ODS]. However, the amount of calcium in a papaya enzyme supplement is likely very small, so do not rely on this product for your daily calcium needs.
How it works
Think of calcium as a key structural component for your bones and a critical signal for your nerves and muscles. It helps maintain bone density through bone mineralization and supports muscle relaxation and nerve signaling [NIH ODS]. For the papaya enzyme component, data is not available to explain its mechanism.
Safety profile
FDA received a total of 592,059 adverse event reports across all supplements, but specific report counts for this product are not available. For calcium specifically, very high intakes can cause constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, and abnormal heart rhythms [NIH ODS]. High calcium intakes might also increase the risk of heart disease and prostate cancer [NIH ODS].
Our recommendation
This product is best used for occasional digestive support, not as a primary calcium source. If you need calcium, look for a dedicated supplement. Be aware that calcium can reduce the absorption of medications such as bisphosphonates, tetracycline antibiotics, and levothyroxine, so take this product at a different time than those drugs [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | 21st Century |
|---|---|
| Serving Size | |
| Contents | 100.0 Chewable Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide