Product Label

Nature's Plus Shot-O-B12 5000 mcg Softgels

Brand: Nature's Plus · Form: SOFTGEL CAPSULE [E0161]

Our assessment

The evidence shows that Nature's Plus Shot-O-B12 5000 mcg Softgels provide a high dose of vitamin B12. However, based on the data provided, this product contains calcium, not B12. Our assessment is that you should verify the label for the actual ingredient list. For bone and nerve health, calcium is essential, but the data shows high intakes may carry risks [NIH ODS].

How it works

Think of calcium as a structural builder for your bones and a signal regulator for your nerves. It supports bone mineralization and density, and it helps your muscles relax and your nerves communicate properly [NIH ODS].

Safety profile

FDA received 592,059 total adverse event reports across all supplements. For calcium specifically, high blood levels can cause poor muscle tone, constipation, nausea, weight loss, extreme tiredness, abnormal heart rhythms, and a high risk of death from heart disease [FDA data] [NIH ODS]. Some research also suggests high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS].

Our recommendation

Check the product label to confirm the ingredients. If it contains calcium, take it with food to improve absorption. Be aware that calcium can reduce the absorption of medications like bisphosphonates, tetracycline antibiotics, and levothyroxine [NIH ODS]. Always consult your pharmacist about timing these medications separately. Data not available for specific B12 content in this product.

AI-assisted analysis. Data sourced from NIH DSLD.

Supplement Facts

BrandNature's Plus
Serving Size
Contents30.0 Softgel(s)
Market StatusOff Market

How to Read This Label

Supplement labels contain several key sections regulated by the FDA:

  • Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
  • Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
  • % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
  • Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
  • Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide

Original Label

View Full DSLD Label (PDF)

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