Life Extension Two-Per-Day Tablets
Brand: Life Extension · Form: TABLET [E0155]
Our assessment
The evidence shows that the Life Extension Two-Per-Day Tablets provide a significant amount of calcium, a mineral essential for bone health and nerve function [NIH ODS]. However, you should be aware that high calcium intakes from supplements carry potential risks that require careful consideration [NIH ODS].
How it works
Think of calcium as a structural builder and a signal messenger. It supports bone mineralization, helping maintain bone density, and is critical for neuromuscular relaxation, allowing your muscles to relax and your nerves to signal properly after contraction [NIH ODS].
Safety profile
FDA received 592,059 total adverse event reports for all dietary supplements. For calcium specifically, some research suggests that high intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Start by assessing your total daily calcium intake from food and other supplements to avoid exceeding the tolerable upper intake level. If you take this product, take it at least 2 hours apart from any medications listed in the safety profile [NIH ODS]. Consult your healthcare provider before starting, especially if you have a history of kidney stones, heart disease, or take thyroid or antibiotic medications [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Life Extension |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide