Bodybuilding.com Signature Amino Plus Energy Grape

Our assessment

The evidence shows that Bodybuilding.com Signature Amino Plus Energy Grape contains Calcium as an ingredient. Our assessment is that while calcium is essential for health, this specific product’s formulation and purpose should be carefully considered. The data provided does not include specific benefits or efficacy studies for this product, so its primary role as an energy and amino acid supplement should be your focus [NIH ODS].

How it works

Calcium functions in your body as a key mineral for bone mineralization, supporting bone density and mineral deposition. It also plays a role in neuromuscular relaxation, helping your muscles relax and your nerves signal properly [NIH ODS]. In this product, the calcium content likely supports these general physiological processes, though the primary intended effect is from the amino acids and energy blend.

Safety profile

The FDA has received a total of 592,059 adverse event reports across all supplement categories, but specific report counts for this product are not available. For calcium specifically, some research suggests that high intakes might increase the risk of heart disease and prostate cancer. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

Our recommendation

Data not available for specific dosing or efficacy studies on this product. Our recommendation is to consider this product as a supplement for energy and amino acids, not as a primary calcium source. If you need to increase your calcium intake for bone health, a targeted calcium supplement is a more reliable option. Always check the label for exact calcium content per serving, and consult your healthcare provider before use, especially if you take any of the medications listed in the safety profile [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide