Vitamin World Melatonin With St. John's Wort

Our assessment

The evidence shows that this product combines two distinct supplements—melatonin and St. John’s Wort—each with different purposes and safety profiles. Based on the data provided, we cannot offer a complete assessment because key information is missing. Data not available for the specific dosage of each ingredient in this combination. Data not available for any specific studies or FDA adverse event reports for this exact product. We advise caution when considering any supplement that combines multiple active ingredients, as interactions and side effects can be unpredictable.

How it works

Melatonin is a hormone that helps regulate your sleep-wake cycle, while St. John’s Wort is traditionally used to support mood. However, because the data provided does not include any studies on this combination, we cannot explain how these two ingredients work together in this specific product. Data not available for studies on this product. Data not available for the mechanism of action for this combination.

Safety profile

Data not available for FDA adverse event reports specific to this product. Data not available for side effects of this combination. Because St. John’s Wort is known to interact with many prescription medications—including antidepressants, birth control pills, and blood thinners—the risks may be significant, but we cannot confirm this from the data provided. Data not available for side effects or report counts.

Our recommendation

Because the data provided does not include dosage information, studies, or safety reports for this specific product, we cannot make a confident recommendation. Data not available for dosage. Data not available for any clinical trials. We suggest speaking with your healthcare provider before using this product, especially if you take any prescription medications. A single-ingredient supplement may be a safer choice until more information is available.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide