21st Century Cranberry Plus Probiotic
Brand: 21st Century · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that while 21st Century Cranberry Plus Probiotic contains ingredients that are generally considered safe, the specific data for this product is limited. Our assessment is based on the active ingredient calcium, which is present in the formulation. Data not available on the specific probiotic strains or cranberry content for this product.
How it works
Think of calcium as a foundation builder for your body. It supports bone density and mineral deposition, which is critical for maintaining strong bones as you age. Calcium also plays a role in neuromuscular relaxation, helping your muscles relax and your nerves signal properly [NIH ODS]. The probiotic component is intended to support digestive health, but specific data on its mechanism for this product is not available.
Safety profile
FDA received 592059 total adverse event reports across all supplements. For calcium specifically, some research suggests that high intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of certain medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
If you are considering this supplement, check the label for the exact amount of calcium per serving. Do not exceed the recommended daily allowance of 1000-1200 mg for most adults from all sources combined. Because calcium can interfere with medications, take this supplement at least 2 hours apart from your prescription drugs. Data not available on the specific probiotic strains, so benefits for digestive health are uncertain. Our recommendation: consult your healthcare provider before starting, especially if you have kidney issues, heart concerns, or take prescription medications [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | 21st Century |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide