21st Century Melatonin 3 mg
Brand: 21st Century · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that 21st Century Melatonin 3 mg is a widely used sleep aid, but the data regarding its specific ingredient profile is limited. For the primary ingredient, melatonin, detailed safety and efficacy data from the provided sources is not available. However, the supplement label lists calcium, which is a mineral with well-documented effects on bone health [NIH ODS].
How it works
Think of calcium as a structural builder for your skeleton and a signal conductor for your nerves. It supports bone density and mineral deposition, and it helps your muscles relax and nerves send signals properly [NIH ODS]. For melatonin’s specific mechanism, data is not available in the provided materials.
Safety profile
FDA received a total of 592,059 adverse event reports across all supplements, though specific counts for this product are not provided. For calcium, which is listed in the product, high intakes might increase the risk of heart disease and prostate cancer. High calcium levels can cause poor muscle tone, poor kidney function, constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Additionally, calcium can reduce the absorption of medications such as bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
You should be cautious with this supplement. Because detailed data on the melatonin content is not available, consult your healthcare provider before starting. If you take any medications, especially antibiotics or thyroid medication, be aware that the calcium in this product could interfere with their absorption [NIH ODS]. Start with the lowest effective dose and monitor for any side effects.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | 21st Century |
|---|---|
| Serving Size | |
| Contents | 90.0 Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide