21st Century Melatonin 3 mg
Brand: 21st Century · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that this product contains 3 mg of melatonin per serving. However, based on the data provided, we cannot assess the benefits or effectiveness of melatonin specifically, as the detailed ingredient data available is for calcium, not melatonin [NIH ODS]. For melatonin-specific health claims and research, data is not available in the provided materials. We can only discuss the calcium component listed in the data set.
How it works
According to the data, calcium functions as a mineral that supports bone mineralization and density, as well as neuromuscular relaxation and nerve signaling [NIH ODS]. For the product's primary ingredient, melatonin, specific mechanisms of action are not included in the provided data.
Safety profile
The FDA has received a total of 592,059 adverse event reports across all supplement categories [FDA data]. For calcium specifically, high intakes may increase the risk of heart disease and prostate cancer. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of medications such as bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Side effect report counts for this specific product are not available.
Our recommendation
Because the provided data does not include specific studies or safety information for melatonin at the 3 mg dose, we cannot make a confident recommendation for this product. If you are considering taking this supplement, consult your healthcare provider about potential interactions with your current medications. For calcium-related concerns, be aware of the absorption issues with other drugs listed above [NIH ODS]. Without melatonin-specific data, we advise caution and suggest seeking products with more complete evidence documentation.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | 21st Century |
|---|---|
| Serving Size | |
| Contents | 220.0 Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide