Major Calcium 600 mg + D3 400 IU
Brand: Major · Form: TABLET [E0155]
Our assessment
Our assessment: For most people, a calcium and vitamin D supplement is a practical way to support bone health, but the evidence requires careful attention to dosage and potential risks. A single tablet provides 600 mg of calcium and 400 IU of vitamin D3, which is a common and generally appropriate starting point for many adults [NIH ODS].
How it works
Think of calcium as the structural building block for your bones, directly supporting bone density and mineral deposition. Vitamin D acts as a master regulator, helping your body absorb that calcium effectively. Together, they also support nerve signaling and muscle relaxation, which is why they are often paired in a single supplement [NIH ODS].
Safety profile
Data not available for specific side effect reports for this exact product. However, based on general FDA data, a total of 592,059 adverse event reports were filed across all supplements. For calcium specifically, high intakes may increase the risk of heart disease and prostate cancer. Side effects from excessive calcium can include constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS] [FDA data].
Our recommendation
Start with one tablet daily, ideally with food to improve absorption. Be aware that calcium can reduce absorption of certain medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin — take this supplement at least two hours apart from those drugs [NIH ODS]. Monitor for digestive discomfort and consult your doctor for a blood test to ensure your calcium and vitamin D levels are in a safe range.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Major |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide