The Vitamin Shoppe D3 10 mcg (400 IU)
Brand: The Vitamin Shoppe · Form: SOFTGEL CAPSULE [E0161] On Market
Our assessment
The evidence shows that The Vitamin Shoppe D3 10 mcg (400 IU) provides a standard, low-dose level of vitamin D. While the product is labeled as vitamin D3, the available data on the active ingredient calcium highlights important considerations. Our assessment: this supplement is appropriate for maintaining baseline levels, but you should not rely on it for significant therapeutic effects at this dose [NIH ODS].
How it works
Vitamin D works closely with calcium to support your body. Think of vitamin D as a master regulator — it helps your immune system respond to threats and supports brain health through neuroplasticity [NIH ODS]. Specifically, the calcium in your body supports bone mineralization to maintain bone density and neuromuscular relaxation for proper nerve signaling and muscle function [NIH ODS].
Safety profile
FDA received a total of 592,059 adverse event reports across all supplement categories. For calcium specifically, side effects can include constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, and abnormal heart rhythms [NIH ODS]. You should also know that calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Some research suggests that high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS].
Our recommendation
Start with this 400 IU dose if you are looking to maintain general health, but be aware that many adults require higher amounts. Do not take this supplement if you are on medications that interact with calcium. If you have a history of kidney stones or heart disease, consult your doctor before starting. For best results, take with food and separate from other medications by at least 2 hours [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | The Vitamin Shoppe |
|---|---|
| Serving Size | |
| Contents | 100.0 Softgel(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide