Metagenics Intrinsi B12-Folate
Brand: Metagenics · Form: TABLET [E0155]
Our assessment
The evidence shows that Metagenics Intrinsi B12-Folate is a combination supplement, but the specific data provided focuses on one of its key ingredients: calcium. Based on the available data, calcium plays a critical role in bone health and nerve function, but we must be cautious about intake levels and potential medication interactions [NIH ODS].
How it works
Think of calcium as a structural building block for your bones and a signal regulator for your nerves. It supports bone mineralization and density, and it helps your muscles relax and your nerves send signals properly [NIH ODS].
Safety profile
FDA received a total of 592,059 adverse event reports across all supplements, though specific counts for this product alone are not available. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer. High levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS] [FDA data]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Start by checking your total daily calcium intake from food and other supplements to avoid exceeding safe levels. If you take any of the listed medications, separate your calcium supplement by at least two hours to avoid absorption issues. For specific dosing and safety guidance on the B12 and folate components of this product, data is not available from the provided sources [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Metagenics |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide