Metagenics St. John's Wort with Folate and B12
Brand: Metagenics · Form: TABLET [E0155]
Our assessment
The evidence shows that Metagenics St. John's Wort with Folate and B12 is a combination product, but the available data does not include specific studies or adverse event reports for this exact formulation. We must rely on general ingredient information. For the calcium component, research suggests high intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. Data on the other ingredients is not available from the provided sources.
How it works
Thinking about the calcium in this product specifically, it acts as a master regulator for your bones. It supports bone density and mineral deposition through a process called bone mineralization, and it also plays a key role in neuromuscular relaxation, helping your muscles relax and nerves signal properly [NIH ODS].
Safety profile
FDA received 592059 total adverse event reports across all supplements, but specific report counts for this product are not available. For calcium, high levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Data not available for a specific recommendation on this product. Because this is a combination supplement with multiple active ingredients, you should consult your healthcare provider before starting it, especially if you take any medications that could interact with calcium [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Metagenics |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide