Sundown B6 100 mg

Our assessment

The evidence shows that while Sundown B6 100 mg is a straightforward supplement, the active ingredient is actually calcium based on the data provided. For a general audience seeking bone and nerve support, calcium is well-established, but the specific dose and form of this product are not available in the data. Our assessment is that you should verify the label for the exact ingredient and dose, as the data only supports a discussion on calcium, not vitamin B6.

How it works

Think of calcium as a structural and signaling mineral. It supports bone density and mineral deposition through bone mineralization, and it is essential for neuromuscular relaxation by supporting muscle relaxation and nerve signaling [NIH ODS]. These mechanisms are critical for maintaining strong bones and proper muscle function.

Safety profile

Data not available for this specific product’s side effects. However, for calcium, high intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. The FDA received a total of 592,059 adverse event reports across all supplements, but specific report counts for this product are not provided [FDA data].

Our recommendation

We recommend you check the product label to confirm the exact ingredient, as the data only supports calcium content. If you are using this for bone health, be aware that calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Start with a low dose and consult your healthcare provider to avoid potential interactions and side effects. Data not available for a specific daily dose recommendation.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide