Metagenics Intrinsi B12-Folate
Brand: Metagenics · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that Metagenics Intrinsi B12-Folate is a specialized supplement designed to support vitamin B12 and folate levels. Our assessment is based on the ingredient profile, which includes calcium as a supporting mineral. Data on calcium indicates it is essential for bone health, but the specific benefits of this product depend on your individual nutritional needs.
How it works
Think of calcium as a foundational mineral for your body. It supports bone mineralization and density, and it plays a role in neuromuscular relaxation and nerve signaling [NIH ODS]. This product combines these minerals with B12 and folate to support cellular energy and red blood cell formation, though specific mechanism data for the full formula is not available beyond the calcium component.
Safety profile
FDA received 592,059 total adverse event reports across all supplements, though specific reports for this product are not isolated. For calcium, high intakes might increase the risk of heart disease and prostate cancer. High blood levels can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce absorption of bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Start by consulting your healthcare provider to confirm you have a deficiency in B12, folate, or calcium. Take this supplement exactly as directed on the label. Be aware of potential interactions with medications like thyroid hormone or antibiotics [NIH ODS]. If you experience constipation, nausea, or unusual tiredness, discontinue use and speak with your doctor. Do not exceed recommended dosages without medical supervision.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Metagenics |
|---|---|
| Serving Size | |
| Contents | 180.0 Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide