NESS Nutritional Enzyme Support System Formula 18 Fat Digest

Our assessment

The evidence shows that NESS Nutritional Enzyme Support System Formula 18 Fat Digest contains calcium, a mineral with well-documented benefits for bone health. However, the data on this specific product is limited. Our assessment is that while calcium is essential, you should not rely on this supplement without considering your total dietary intake and potential risks [NIH ODS].

How it works

Think of calcium as a master builder for your skeleton. It supports bone density and mineral deposition, which is critical for maintaining strong bones as you age. Calcium also plays a role in neuromuscular relaxation, helping your muscles relax and your nerves signal properly [NIH ODS].

Safety profile

FDA has received a total of 592,059 adverse event reports across all dietary supplements, though specific report counts for this product are not available. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer. High levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS] [FDA data]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

Our recommendation

Start by assessing your total daily calcium intake from food and other supplements. If you take this product, be aware of the potential for high calcium levels and the interactions with important medications. We recommend consulting your healthcare provider before starting this supplement, especially if you take any of the listed medications or have a history of kidney problems [NIH ODS]. Data on the specific enzyme blend in this product is not available.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide