Life Extension Optimized Folate L-Methylfolate 1000 mcg
Brand: Life Extension · Form: TABLET [E0155]
Our assessment
The evidence shows that this product contains L-methylfolate, not calcium. For calcium specifically, our assessment is that it is essential for bone mineralization and nerve signaling [NIH ODS]. However, the data provided does not include specific findings on L-methylfolate. Data not available for the specific ingredient in this product.
How it works
Think of calcium as a structural builder for your skeleton. It supports bone density and mineral deposition, and it also helps your muscles relax and your nerves send signals properly [NIH ODS]. The mechanism of L-methylfolate in this product is not described in the data provided.
Safety profile
FDA received 592,059 total adverse event reports across all supplements. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. High levels can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Data not available for side effects of L-methylfolate from the provided FDA data.
Our recommendation
Because the data provided does not include information on L-methylfolate, you should speak with your healthcare provider before taking this supplement. For calcium, you should be aware that it can reduce the absorption of bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Data not available for a specific recommendation on this product.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Life Extension |
|---|---|
| Serving Size | |
| Contents | 100.0 Vegetarian Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide