Douglas Laboratories Melatonin P.R. Prolonged-Release 3 mg
Brand: Douglas Laboratories · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that prolonged-release melatonin, like the Douglas Laboratories 3 mg product, can be a useful tool for supporting sleep onset and maintenance. However, based on the data provided, the specific ingredient listed under the NIH ODS section is Calcium, not Melatonin. Data on melatonin’s mechanism, safety, and interactions is not available in the provided information. Our assessment is that we must rely only on the data provided, which pertains to Calcium.
How it works
Think of calcium as a structural support for your bones and a signal regulator for your nerves and muscles. It works through bone mineralization to support bone density and mineral deposition, and through neuromuscular relaxation to support muscle relaxation and nerve signaling [NIH ODS].
Safety profile
FDA received 592,059 total adverse event reports for all supplements in this dataset. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer according to some research. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS] [FDA data].
Our recommendation
Data not available for melatonin-specific recommendations. Based on the calcium data provided, you should be cautious about high calcium intakes. Calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Do not exceed recommended dietary allowances without professional guidance.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Douglas Laboratories |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide