Life Extension Melatonin IR/XR
Brand: Life Extension · Form: CAPSULE [E0159]
Our assessment
The evidence shows that calcium is essential for bone health, but supplementation requires careful consideration of your overall intake. Data on calcium from food and supplements is well-documented, and the risks are real if you exceed recommended levels [NIH ODS].
How it works
Think of calcium as a structural builder for your bones. It supports bone density and mineral deposition, and it also helps your muscles relax and your nerves signal properly [NIH ODS].
Safety profile
FDA received 592,059 total adverse event reports across all supplements. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer. High levels in your blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS] [FDA data].
Our recommendation
You should aim to get calcium from food first. If you supplement, be aware that calcium can reduce absorption of medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Data on the specific product Life Extension Melatonin IR/XR is not available. Consult your healthcare provider before adding calcium to your routine.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Life Extension |
|---|---|
| Serving Size | |
| Contents | 60.0 Capsule(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide