21st Century Melatonin 10 mg
Brand: 21st Century · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that melatonin is a popular supplement for sleep support, but the 10 mg dose you are asking about is significantly higher than what is typically recommended. Data on melatonin specifically is limited in the provided information, and we must rely on what is available. For the ingredient calcium, which is listed on the label, the data confirms a clear role in bone health but also carries important safety considerations [NIH ODS].
How it works
Think of calcium as a building block for your bones. It supports bone density and mineral deposition, which is crucial for maintaining a strong skeleton. Additionally, calcium plays a role in neuromuscular relaxation, helping your muscles relax and your nerves signal properly [NIH ODS]. For melatonin’s specific mechanism, data is not available in the provided materials.
Safety profile
For calcium, safety data indicates that high intakes might increase the risk of heart disease and prostate cancer. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. The FDA received a total of 592,059 adverse event reports across all supplements, though specific report counts for melatonin or this product are not available in the provided data [FDA data].
Our recommendation
Start with a much lower dose of melatonin, typically 0.5 to 3 mg, and work with your healthcare provider to find the right amount for you. For calcium, be cautious about exceeding the recommended dietary allowance, as high levels carry risks. Also, be aware that calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, and levothyroxine [NIH ODS]. Always consult your doctor before starting a new supplement, especially at a high dose like 10 mg [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | 21st Century |
|---|---|
| Serving Size | |
| Contents | 120.0 Cherry Flavor Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide