NESS Nutritional Enzyme Support System Formula 701 Circulatory Support

Our assessment

The evidence shows that the NESS Nutritional Enzyme Support System Formula 701 Circulatory Support contains calcium as an ingredient. For this mineral, our assessment is that it plays a vital role in bone health, but you need to be aware of specific risks and medication interactions before taking it [NIH ODS].

How it works

Think of calcium as a structural builder and a signal conductor. It supports bone density and mineral deposition, which is essential for a strong skeleton. Additionally, it supports muscle relaxation and nerve signaling, helping your nervous system communicate effectively [NIH ODS].

Safety profile

Data not available for this specific product's side effects. However, for the ingredient calcium, some research suggests that high intakes might increase the risk of heart disease and prostate cancer. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. The FDA has received a total of 592,059 adverse event reports across all dietary supplements, but this number is not specific to this product [FDA data].

Our recommendation

We recommend you consult with your healthcare provider before taking this product, especially if you take medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, or phenytoin, as calcium can reduce their absorption [NIH ODS]. Be cautious not to exceed recommended intakes, as high levels carry significant health risks [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide