HempWorx CBD+ Melatonin

Our assessment

The evidence shows that this product combines CBD with melatonin, but the data provided focuses on the calcium content. For calcium specifically, our assessment is that it is essential for bone health, but you must be cautious with dosing. The data confirms that high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS].

How it works

Think of calcium as a building block for your bones. It supports bone density and mineral deposition, and it also helps your muscles relax and your nerves send signals properly [NIH ODS]. For the CBD and melatonin components of this product, data on their specific mechanisms are not available in the provided information.

Safety profile

FDA received a total of 592,059 adverse event reports across all products. For calcium specifically, side effects from high blood and urine levels include poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Data on side effects specific to CBD or melatonin in this product is not available.

Our recommendation

Because this product contains both CBD and melatonin, and data on these specific ingredients is not provided, we cannot make a confident recommendation for its use. For calcium, you should be aware that high intakes carry significant risks [NIH ODS]. Consult your healthcare provider before starting this supplement, especially if you take any prescription medications or have a history of kidney or heart conditions.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide