Metagenics St. John's Wort with Folate and B12
Brand: Metagenics · Form: TABLET [E0155]
Our assessment
The evidence shows that this product combines St. John's Wort with Folate and B12. Data on the specific interactions of this combination is limited. We must be very clear: St. John's Wort is a potent herb with significant drug interactions, and you should consult your doctor before use, especially if you take any prescription medications. The specific clinical benefits of this particular blend are not directly supported by the provided data.
How it works
St. John's Wort is traditionally used to support mood, though the exact mechanism is not fully detailed in the provided data. The added Folate and B12 are essential for nerve health and the production of red blood cells. Folate helps your body form DNA and supports cell division, while B12 is crucial for maintaining healthy nerve cells and helping to make DNA [NIH ODS].
Safety profile
The FDA has received a total of 592059 adverse event reports across all dietary supplements, though this number is not specific to this product [FDA data]. A critical safety concern is that St. John's Wort is known to interact with many medications, including antidepressants, birth control pills, and blood thinners. Data on side effects for the St. John's Wort component is not available from the provided FDA data. For the calcium component (which is not listed in this product's ingredients), high levels can cause poor muscle tone, constipation, and nausea [NIH ODS].
Our recommendation
We recommend you proceed with extreme caution. Because the provided data lacks specific clinical studies on this exact combination and does not detail the side effects or drug interaction profile for St. John's Wort, you should not start taking this supplement without first speaking to your doctor or pharmacist. They can review your current medications and health status to ensure this product is safe and appropriate for you.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Metagenics |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide