The Vitamin Shoppe 5-HTP with Vitamin B6 100 mg
Brand: The Vitamin Shoppe · Form: CAPSULE [E0159]
Our assessment
The evidence shows that this product combines 5-HTP and Vitamin B6, but the data provided primarily covers the Vitamin B6 component. For Vitamin B6, the data supports its role in bone mineralization and neuromuscular relaxation, but you should be aware of significant safety considerations [NIH ODS].
How it works
Think of Vitamin B6 as a support worker for your nervous system and bones. It helps your body with bone mineralization, which is the process of depositing minerals into bone tissue to keep them strong. It also supports neuromuscular relaxation, meaning it helps your muscles relax and your nerves send signals properly [NIH ODS].
Safety profile
The FDA has received a total of 592,059 adverse event reports across all supplements. For Vitamin B6 specifically, the data warns that high levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS] [FDA data].
Our recommendation
Data not available for specific dosing or interaction warnings for the 5-HTP component. For the Vitamin B6 component, you should be cautious about taking this supplement if you are on medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, or phenytoin, as calcium can reduce their absorption [NIH ODS]. Given the serious side effects listed, we recommend consulting your healthcare provider before starting this product.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | The Vitamin Shoppe |
|---|---|
| Serving Size | |
| Contents | 60.0 Capsule(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide