Natural Factors Stress-Relax Melatonin 5 mg
Brand: Natural Factors · Form: TABLET [E0155]
Our assessment
The evidence shows that this product contains 5 mg of melatonin per serving. Our assessment is that this is a high dose, as most adults respond well to doses between 0.5 mg and 3 mg. Starting with a lower strength is often more effective and minimizes side effects. Data on the specific ingredient calcium is not available for this product, so we cannot assess its role here.
How it works
Melatonin acts as a master regulator of your sleep-wake cycle, signaling to your body that it is time to rest. It works by binding to receptors in the brain that help promote drowsiness and regulate your internal clock. For calcium, which is a separate ingredient not listed in this product, its mechanism involves bone mineralization and neuromuscular relaxation [NIH ODS].
Safety profile
FDA has received a total of 592,059 adverse event reports across all dietary supplements, but specific report counts for this product are not available. For melatonin, common side effects at high doses can include daytime drowsiness, dizziness, or headaches. Regarding calcium, high intakes may increase the risk of heart disease and prostate cancer, and can cause symptoms such as constipation, nausea, and abnormal heart rhythms [NIH ODS] [FDA data].
Our recommendation
We recommend starting with a lower melatonin dose (0.5 mg to 3 mg) to assess your tolerance. If you choose to use this 5 mg product, take it only 30 to 60 minutes before bedtime. Do not drive or operate machinery after taking it. Consult your healthcare provider before starting any new supplement, especially if you take medications or have a medical condition. Data on specific interactions for this product is not available.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Natural Factors |
|---|---|
| Serving Size | |
| Contents | 180.0 Chewable Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide