21st Century Calcium Citrate Petites +D3
Brand: 21st Century · Form: TABLET [E0155]
Our assessment
The evidence shows that calcium, as found in 21st Century Calcium Citrate Petites +D3, is a well-established mineral for bone health. Our assessment is that this supplement can be a useful option for supporting your bone density, but you need to be aware of the specific safety considerations and potential interactions. Data on the exact amount of calcium and vitamin D per serving is not available in the provided data.
How it works
Think of calcium as a key building block for your skeleton. It supports bone mineralization, which is the process of depositing minerals into your bone matrix to maintain density and strength. Additionally, calcium plays a critical role in neuromuscular relaxation, helping your muscles relax and your nerves signal properly [NIH ODS].
Safety profile
The FDA has received a total of 592,059 adverse event reports for this product. While many people tolerate calcium supplements well, high levels of calcium in your blood and urine can cause serious issues including poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [FDA data]. Some research also suggests that high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS].
Our recommendation
Our recommendation is to approach this supplement with caution. Be aware that calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. To minimize risk, do not exceed the recommended dose on the label and consult your doctor before starting, especially if you have a history of kidney stones, heart disease, or take any of the listed medications. Data not available for the specific amount of calcium and vitamin D per serving to give a more precise dosing recommendation.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | 21st Century |
|---|---|
| Serving Size | |
| Contents | 200.0 Coated Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide