21st Century Calcium Citrate +D3 Maximum
Brand: 21st Century · Form: TABLET [E0155]
Our assessment
The evidence shows that this combination of calcium and vitamin D3 is well-supported for bone health, but you need to be careful with dosing. Our assessment: This product can help you meet your daily calcium needs, but you should verify your total intake from all sources to avoid exceeding safe levels [NIH ODS].
How it works
Think of calcium as a building block for your bones, supporting bone mineralization and density. Vitamin D3 helps your body absorb that calcium. Together, they support neuromuscular relaxation and nerve signaling [NIH ODS].
Safety profile
FDA received 592059 total adverse event reports across all supplement categories. For calcium specifically, high intakes may increase the risk of heart disease and prostate cancer. Side effects from too much calcium include constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS] [FDA data].
Our recommendation
Start by checking your total daily calcium intake from food and supplements. Take this product with food and separate it from medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin by at least 2 hours [NIH ODS]. Data not available on the exact dose of calcium and vitamin D3 in this specific product.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | 21st Century |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide