Divine Health Serene-3

Our assessment

The evidence shows that Serene-3 contains calcium, a mineral with well-documented roles in the body. However, we must be clear: based on the data provided, we cannot assess the specific benefits of the Serene-3 formulation itself, as no studies on this exact product are included in the data. Our analysis focuses on the ingredient as listed on the label.

How it works

Think of calcium as a structural foundation — it supports bone density and mineral deposition through bone mineralization [NIH ODS]. It also plays a key role in neuromuscular relaxation, helping your muscles relax and your nerves signal properly [NIH ODS].

Safety profile

The FDA has received a total of 592,059 adverse event reports across all supplements, though specific report counts for Serene-3 are not available [FDA data]. For calcium specifically, high intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. Very high levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

Our recommendation

Data not available on the exact formulation or dosage of Serene-3, so we cannot provide a specific dosage recommendation. If you are considering this product, we suggest you first review your total calcium intake from food and other supplements. Because of the potential for serious side effects and drug interactions, we recommend speaking with your healthcare provider before starting this supplement, especially if you take any medications or have a history of kidney problems [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide