PharmAssure Calcium, Magnesium & Zinc

Our assessment

The evidence shows that PharmAssure Calcium, Magnesium & Zinc provides a combination of minerals that support bone health and nerve function. Calcium is essential for bone mineralization and neuromuscular relaxation [NIH ODS]. However, you need to be aware of the potential risks associated with high calcium intake, as the data includes a significant number of adverse event reports.

How it works

Think of calcium as a structural building block for your bones and a signal regulator for your nerves. It supports bone density and helps muscles relax after contraction [NIH ODS]. The combination with magnesium and zinc is intended to support these processes, though specific data on the synergy for this exact product is not available.

Safety profile

FDA received 592,059 total adverse event reports for this product category. Side effects from high calcium intake include constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [FDA data] [NIH ODS]. High levels of calcium in the blood and urine can also cause poor muscle tone, poor kidney function, and low phosphate levels [NIH ODS]. Some research suggests high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. Calcium can also reduce the absorption of medications such as bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

Our recommendation

Start by evaluating your dietary calcium intake before adding this supplement. If you take it, follow the label dosing carefully and do not exceed the RDA for your age group. Take it separately from the medications listed above to avoid absorption issues [NIH ODS]. Data on the exact dosage for this specific product is not available, so consult your healthcare provider to determine if this combination is right for you.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide