21st Century Calcium 600+D
Brand: 21st Century · Form: SUPPLEMENT FORM, OTHER [E0172] On Market
Our assessment
The evidence shows that this supplement provides 600 IU of vitamin D alongside calcium to support bone health. Our assessment: based on the data, this is a standard formulation for individuals who need to increase their calcium intake, but you must be aware of the specific risks and interactions associated with calcium supplementation.
How it works
Calcium works as a bone mineralizer, directly supporting bone density and mineral deposition, and also plays a role in neuromuscular relaxation and nerve signaling [NIH ODS]. The added vitamin D helps your body absorb this calcium more effectively.
Safety profile
FDA received 592,059 adverse event reports across all products, though data is not available for this specific product alone. You should be aware that high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Our recommendation: take this supplement only if you have a confirmed need for additional calcium, such as a low dietary intake or a diagnosed deficiency. To avoid drug interactions, take this supplement at least two hours apart from any medications listed in the safety profile. Monitor for symptoms like constipation or nausea, and do not exceed the recommended dose on the label without consulting your healthcare provider.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | 21st Century |
|---|---|
| Serving Size | |
| Contents | 200.0 Caplet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide