Natural Factors Stress-Relax Melatonin 1 mg

Our assessment

The evidence shows that calcium is a foundational mineral for bone health and nerve function. The data confirms that adequate intake supports bone mineralization and neuromuscular relaxation [NIH ODS]. However, for a product like Natural Factors Stress-Relax Melatonin 1 mg, calcium is not listed as an active ingredient, so its benefits do not apply here. We must focus on the data provided.

How it works

Think of calcium as a structural builder for your skeleton and a signal regulator for your nerves and muscles. It supports bone density through mineral deposition and helps your muscles relax and your nerves send signals properly [NIH ODS]. For this specific product, the mechanism of the active ingredient (melatonin) is not detailed in the provided data, so we cannot explain it.

Safety profile

FDA received a total of 592,059 adverse event reports across all supplements, but specific report counts for this product are not available. For calcium specifically, side effects from high intake include poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. High calcium intakes might also increase the risk of heart disease and prostate cancer [NIH ODS]. Data not available for side effects of this specific product.

Our recommendation

Because the provided data does not include details on melatonin or the specific formulation of Natural Factors Stress-Relax Melatonin 1 mg, we cannot make a confident recommendation for this product. For calcium generally, you should be aware that it can reduce the absorption of medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Speak with your healthcare provider before starting any new supplement, especially if you take prescription medications.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide