Life Extension Melatonin 3 mg

Our assessment

The evidence shows that calcium is a critical mineral for bone health, but the data does not support taking it in the form of a melatonin supplement. Since this product is labeled as Life Extension Melatonin 3 mg, our assessment is that calcium is not a primary ingredient here. For calcium specifically, the data indicates it supports bone mineralization and neuromuscular relaxation [NIH ODS]. However, you should not expect a calcium benefit from a melatonin product. Data not available for this specific product's combination.

How it works

Think of calcium as a key structural component — it is essential for bone density and mineral deposition, and it also supports muscle relaxation and nerve signaling [NIH ODS]. The data confirms these roles, but again, this mechanism applies to calcium supplements, not to the melatonin product you are asking about. For the melatonin product itself, mechanism data is not provided.

Safety profile

FDA received 592,059 total adverse event reports across all dietary supplements. For calcium specifically, high intakes may increase the risk of heart disease and prostate cancer. High levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce absorption of bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. No specific side effect report counts for calcium were provided in the FDA data.

Our recommendation

Our recommendation is to confirm that you are taking a calcium supplement if that is your goal, not a melatonin product. If you need calcium, the data supports using it for bone health, but you should be aware of the safety risks at high doses and the medication interactions listed above [NIH ODS]. For the Life Extension Melatonin 3 mg product, data on its specific effects, dosing, and safety is not available in the provided information. Always consult your healthcare provider before starting any new supplement.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide