Life Extension Melatonin 500 mcg
Brand: Life Extension · Form: CAPSULE [E0159]
Our assessment
Our assessment is that the evidence for calcium supplements is clear on bone health, but you need to be cautious with dosing. The data shows that high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS]. This is a supplement where more is not better.
How it works
Think of calcium as a structural builder for your skeleton. It supports bone density and mineral deposition, and it also plays a role in neuromuscular relaxation and nerve signaling [NIH ODS]. Your body relies on a steady supply to keep these systems running smoothly.
Safety profile
FDA received 592,059 total adverse event reports across all supplements. For calcium specifically, high levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS] [FDA data]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Our recommendation is to prioritize getting calcium from food sources first. If you use a supplement, avoid exceeding the recommended daily allowance and take it separately from other medications by at least two hours to prevent absorption issues [NIH ODS]. Data on the specific interaction between calcium and the Life Extension Melatonin 500 mcg product is not available.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Life Extension |
|---|---|
| Serving Size | |
| Contents | 200.0 Vegetarian Capsule(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide