Product Label

The Vitamin Shoppe 5-HTP with Vitamin B6 100 mg

Brand: The Vitamin Shoppe · Form: CAPSULE [E0159]

Our assessment

The evidence shows that this product combines 5-HTP with Vitamin B6, but the data we have is limited to the calcium content in the Vitamin B6 component. Our assessment is that while 5-HTP is often used for mood and sleep support, we do not have specific data on its efficacy or long-term safety from the provided sources. The data on calcium, an ingredient in this product, is well-documented [NIH ODS].

How it works

Think of calcium as a structural and signaling powerhouse. It supports bone density through mineralization and is essential for neuromuscular relaxation and proper nerve signaling [NIH ODS]. For the 5-HTP component, data on its specific mechanism is not available from the provided sources. The Vitamin B6 in this product is included as a co-factor, but specific data on its role here is not provided.

Safety profile

Data not available for 5-HTP or Vitamin B6 from the provided FDA adverse event report data. The FDA received a total of 592,059 adverse event reports across all supplements, but specific report counts for this product's ingredients are not listed [FDA data]. For the calcium component, high intakes might increase the risk of heart disease and prostate cancer. High levels can cause poor muscle tone, poor kidney function, constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of medications like bisphosphonates, tetracycline antibiotics, and levothyroxine [NIH ODS].

Our recommendation

Start by consulting your doctor before taking this supplement, especially if you take any medications or have a history of heart or kidney conditions. Data on the specific benefits and risks of 5-HTP is not available from the provided sources. If you choose to take it, be aware of the potential side effects from the calcium component and monitor for any unusual symptoms [NIH ODS].

AI-assisted analysis. Data sourced from NIH DSLD.

Supplement Facts

BrandThe Vitamin Shoppe
Serving Size
Contents60.0 Capsule(s)
Market StatusOff Market

How to Read This Label

Supplement labels contain several key sections regulated by the FDA:

  • Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
  • Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
  • % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
  • Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
  • Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide

Original Label

View Full DSLD Label (PDF)

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