Life Extension Melatonin 300 mcg 6 Hour Timed Release
Brand: Life Extension · Form: TABLET [E0155]
Our assessment
The evidence shows that melatonin, when used appropriately, is a well-studied supplement for supporting sleep. This specific product from Life Extension provides 300 mcg (0.3 mg) in a timed-release formula, which is a very low dose designed to mimic the body's natural melatonin production. For most adults, this is a safe and gentle starting point for occasional sleep support [FDA data].
How it works
Think of melatonin as your body's natural sleep signal. It is a hormone that regulates your circadian rhythm—your internal 24-hour clock. The timed-release formulation in this product is designed to release melatonin gradually over 6 hours, helping you not only fall asleep but also stay asleep through the night. Data on the specific mechanism of melatonin for sleep timing is well-documented, though exact numbers for this low dose are limited [NIH ODS].
Safety profile
FDA has received a total of 592,059 adverse event reports across all supplements, but specific report counts for melatonin at this 300 mcg dose are not available. At low doses like this, melatonin is generally well-tolerated. Common side effects from higher doses can include drowsiness, headache, dizziness, or nausea, but these are less likely at 300 mcg. Because this is a timed-release product, you may feel some residual drowsiness in the morning if you do not allow for a full 8-hour sleep window [FDA data].
Our recommendation
Start by taking one tablet 30 to 60 minutes before your desired bedtime. This 300 mcg dose is an excellent option for those new to melatonin or sensitive to supplements. Because it is timed release, ensure you have at least 6 to 8 hours available for sleep to avoid morning grogginess. If you have a history of autoimmune disorders or are taking blood thinners, consult your doctor before use [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Life Extension |
|---|---|
| Serving Size | |
| Contents | 100.0 Vegetarian Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide