Sundown Naturalist Melatonin 300 mcg

Our assessment

The evidence shows that Sundown Naturalist Melatonin 300 mcg is a low-dose melatonin supplement. However, the data provided does not contain specific studies or safety information for melatonin itself. What we do have is data for the mineral calcium, which is not the primary active ingredient in this product. Based on the available data, we cannot assess the effectiveness or safety of this specific melatonin product. For calcium, our assessment is that it supports bone mineralization and neuromuscular relaxation [NIH ODS].

How it works

Think of calcium as a structural building block and a signaling molecule. It supports bone density and mineral deposition, and it also helps your muscles relax and your nerves transmit signals properly [NIH ODS]. You should be aware that calcium can reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

Safety profile

For calcium, some research suggests that high intakes might increase the risk of heart disease and prostate cancer. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. The FDA has received a total of 592,059 adverse event reports for all dietary supplements, but specific report counts for this product or melatonin are not available [FDA data].

Our recommendation

Data not available to make a specific recommendation for Sundown Naturalist Melatonin 300 mcg. For calcium, start with dietary sources and consider supplementation only if your intake is low. Be cautious with high-dose calcium supplements and discuss potential medication interactions with your doctor [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide