Sundown Naturals B12 1000 mcg
Brand: Sundown Naturals · Form: TABLET [E0155]
Our assessment
The evidence shows that Sundown Naturals B12 1000 mcg provides a high-dose form of vitamin B12. However, the data provided focuses on calcium, not vitamin B12, which means specific clinical information for this supplement is limited. Our assessment is that you should verify the label to confirm the exact form of B12 (such as cyanocobalamin or methylcobalamin) for optimal absorption. Data not available for B12-specific clinical trials from the provided list.
How it works
While data for B12 is not provided, the ingredient calcium is described as supporting bone mineralization through bone density and mineral deposition, and neuromuscular relaxation by supporting muscle relaxation and nerve signaling [NIH ODS]. This mechanism is distinct from B12, which typically supports energy metabolism and red blood cell formation. For B12-specific action, data not available.
Safety profile
FDA received a total of 592,059 adverse event reports across all supplements, but specific report counts for this product are not available. For the ingredient calcium, side effects reported at high levels include constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and poor muscle tone [NIH ODS]. Calcium can also reduce absorption of medications such as bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. For B12-specific side effects, data not available.
Our recommendation
Our recommendation is to review the product label carefully to confirm the B12 form. If you are taking calcium-containing supplements or medications, be aware of potential absorption issues [NIH ODS]. For a general audience, 1000 mcg of B12 is a common maintenance dose, but we advise consulting your healthcare provider before starting any new supplement. Data not available to make a stronger recommendation for this specific product.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Sundown Naturals |
|---|---|
| Serving Size | |
| Contents | 60.0 Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide