Signature Care High Potency Iron 65 mg
Brand: Signature Care · Form: TABLET [E0155] On Market
Our assessment
Our assessment: For a product containing 65 mg of iron, the evidence shows that calcium is a key interacting mineral you need to be aware of. Iron and calcium can compete for absorption in your body, which means taking them together can reduce how much iron you actually absorb. The data confirms that calcium supplements may reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
How it works
Think of calcium as a dual-role mineral — it supports bone mineralization and density while also helping with neuromuscular relaxation and nerve signaling [NIH ODS]. For you, taking this iron supplement, it is important to understand that calcium can interfere with iron absorption if taken at the same time. The mechanism involves competition for transport proteins in your digestive tract, so spacing your calcium intake away from your iron dose by at least two hours can help maximize the benefit of both minerals.
Safety profile
FDA received a total of 592,059 adverse event reports across all supplements. For calcium specifically, data not available on exact report counts for this ingredient alone. However, high levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Some research also suggests that high calcium intakes might increase the risk of heart disease and prostate cancer [NIH ODS].
Our recommendation
Our recommendation: If you are taking this iron supplement, do not take it at the same time as calcium-rich foods or calcium supplements. Space them by at least two hours to avoid absorption competition. Be aware that calcium can reduce absorption of certain medications, so if you take any prescription drugs, check with your pharmacist about timing. Do not exceed the recommended dose of iron without medical supervision, and know that data on specific interactions between this exact product and calcium is not available beyond the general guidance provided [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Signature Care |
|---|---|
| Serving Size | |
| Contents | 30.0 Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide