NOW Probiotic Defense
Brand: NOW · Form: CAPSULE [E0159] On Market
Our assessment
The evidence shows that NOW Probiotic Defense is a supplement containing calcium, and we need to focus on that ingredient’s profile. For general health, calcium is essential, but high intakes carry risks. Our assessment: you should only use this product if you have a confirmed need for additional calcium, as unmonitored supplementation can lead to serious health issues. Data not available on the specific probiotic strains in this product.
How it works
Calcium is a master regulator for your body. It supports bone mineralization and density, and it is critical for neuromuscular relaxation and proper nerve signaling [NIH ODS]. Think of it as the key mineral that helps your muscles relax after contraction and keeps your skeleton strong.
Safety profile
FDA has received 592,059 total adverse event reports for products in this category, though this number includes all supplements, not just this specific one [FDA data]. For calcium specifically, high intakes may increase the risk of heart disease and prostate cancer. High levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Our recommendation: Do not take this supplement without consulting your doctor. If you are not calcium deficient, adding extra calcium may do more harm than good. If you do take it, separate it from any medications by at least two hours to avoid absorption issues [NIH ODS]. For most adults, getting calcium from food is safer and more effective than supplements.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | NOW |
|---|---|
| Serving Size | |
| Contents | 90.0 Veg Capsule(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide