GNC Pro Performance Amino Burst 3000

Our assessment

The evidence shows that GNC Pro Performance Amino Burst 3000 contains calcium, a mineral essential for bone health and muscle function. However, our assessment is that you should be cautious with this product. The data does not provide specific ingredient amounts for the calcium content, making it difficult to determine if the dose is appropriate for you. Many people get enough calcium from diet alone, and adding a supplement without need can pose risks [NIH ODS].

How it works

Calcium acts as a master regulator for your body. It supports bone mineralization and density, which is critical for preventing fractures as you age. It also plays a key role in neuromuscular relaxation, helping your muscles relax and your nerves signal properly after exertion [NIH ODS].

Safety profile

FDA received a total of 592,059 adverse event reports across all products, but specific report counts for this supplement are not available. The data shows that high calcium intakes might increase the risk of heart disease and prostate cancer. Side effects from excessive calcium include poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS] [FDA data]. Additionally, calcium can reduce the absorption of medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].

Our recommendation

Data not available on the exact calcium dose in this product, so we cannot recommend it as a reliable calcium supplement. For most adults, the RDA for calcium is 1,000–1,200 mg daily from food and supplements combined. If you are considering this product, check with your healthcare provider first, especially if you take any of the medications listed above. A targeted calcium supplement with a known dose is a safer choice [NIH ODS].

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide