NESS Nutritional Enzyme Support System Formula 20 Digest

Our assessment

The evidence shows that NESS Nutritional Enzyme Support System Formula 20 Digest contains the mineral Calcium. Our assessment is that this product may help you meet your calcium needs, but you must be aware of the specific risks and interactions associated with this ingredient. The data provided does not include any enzyme-specific studies for this formula, so we are focusing on the calcium content.

How it works

Calcium is a critical mineral for your body. It functions as a master regulator for bone mineralization, helping to support bone density and mineral deposition. It also supports neuromuscular relaxation and nerve signaling [NIH ODS]. Think of it as the foundation for strong bones and proper muscle function.

Safety profile

The FDA has received a total of 592,059 adverse event reports for all dietary supplements, though specific reports for this product are not available. For calcium specifically, the data shows that high intakes might increase the risk of heart disease and prostate cancer. High levels in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of several medications, including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS]. Data not available for side effects specific to this product.

Our recommendation

We recommend you consult with your healthcare provider before taking this product, especially if you take any medications for osteoporosis, thyroid conditions, or infections. Do not exceed the recommended dose on the label, and be aware that high calcium intake carries significant risks [NIH ODS]. If you have a history of kidney disease, heart disease, or prostate cancer, seek professional medical advice first. Data not available to confirm the efficacy of the enzyme blend in this formula.

Supplement labels contain several key sections regulated by the FDA:

• Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
• Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
• % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
• Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
• Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.

Source: FDA Dietary Supplement Labeling Guide