Natural Factors B12 Methylcobalamin High Potency 5000 mcg
Brand: Natural Factors · Form: TABLET [E0155]
Our assessment
The evidence shows that Methylcobalamin (Vitamin B12) at 5000 mcg is a high-dose supplement typically used to address a diagnosed deficiency. Your specific product is from Natural Factors, but we have no data on its manufacturing or purity. Our assessment is based on the ingredient's general profile, and we must note that specific data for this product is limited.
How it works
Vitamin B12 is a water-soluble vitamin that plays a key role in red blood cell formation, neurological function, and DNA synthesis. Methylcobalamin is the active form of B12 that your body can use directly. It works as a cofactor for enzymes that convert homocysteine to methionine, a process critical for brain and nerve health [NIH ODS].
Safety profile
Data not available for this specific product. For all dietary supplements, the FDA has received a total of 592059 adverse event reports across all products. No specific side effect data was provided for B12 or this brand. Generally, Vitamin B12 is considered safe, but high blood levels of B12 can indicate an underlying condition. Side effects are uncommon but may include mild diarrhea or itching [FDA data].
Our recommendation
We do not recommend starting a 5000 mcg dose without first confirming a B12 deficiency through a blood test. For most people, lower doses (e.g., 50–100 mcg) are sufficient for maintenance. If you have been advised by your healthcare provider to take this high potency, it is appropriate. Always take B12 supplements with food for better absorption [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Natural Factors |
|---|---|
| Serving Size | |
| Contents | 60.0 Chewable Tablet(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide