Natural Factors BioSil Bone CollaGenizer Matrix with ch-OSA Advanced Collagen Generator
Brand: Natural Factors · Form: CAPSULE [E0159]
Our assessment
The data indicates that this product contains calcium, a mineral essential for bone health. Our assessment: calcium is a foundational nutrient for bone mineralization, but it works best alongside other bone-supporting nutrients. The data does not provide specific information on the other ingredients in this formula, so we must focus on what we know from the evidence provided [NIH ODS].
How it works
Think of calcium as a structural building block for your skeleton. It supports bone density and mineral deposition, and it also plays a role in muscle relaxation and nerve signaling [NIH ODS]. For your bones, calcium is deposited into the matrix to keep them strong and dense, but the process requires adequate vitamin D and other co-factors to be effective.
Safety profile
The FDA received a total of 592,059 adverse event reports across all supplements, though specific data for this product is not available. For calcium specifically, some research suggests that high intakes might increase the risk of heart disease and prostate cancer. High levels of calcium in the blood and urine can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent need to urinate, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Data not available on specific report counts for this product’s side effects.
Our recommendation
For most adults, aim for 1,000–1,200 mg of total calcium daily from food and supplements combined. To maximize absorption, take calcium supplements with food and avoid taking them at the same time as medications like bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, or phenytoin, as calcium can reduce their absorption [NIH ODS]. Start with a lower dose and monitor for any digestive discomfort. Always consult your healthcare provider before starting a new supplement, especially if you have a history of kidney stones or heart conditions.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Natural Factors |
|---|---|
| Serving Size | |
| Contents | 40.0 Vegetarian Capsule(s) |
| Market Status | Off Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide