Nature Made Vitamin B12 1000 mcg
Brand: Nature Made · Form: TABLET [E0155] On Market
Our assessment
The evidence shows that calcium is essential for bone health, but the data on supplementation is nuanced. For most adults, the primary goal should be meeting the RDA through diet, as high supplemental intakes carry specific risks [NIH ODS].
How it works
Think of calcium as a structural foundation — it supports bone density and mineral deposition, and it is critical for muscle relaxation and nerve signaling [NIH ODS]. Your body tightly regulates calcium levels, and when you do not get enough from your diet, it will leach calcium from your bones to maintain normal function.
Safety profile
FDA received a total of 592,059 adverse event reports across all supplements. Specific to calcium, high intakes are linked to risks of heart disease and prostate cancer. High blood and urine calcium levels can cause poor muscle tone, poor kidney function, low phosphate levels, constipation, nausea, weight loss, extreme tiredness, frequent urination, abnormal heart rhythms, and a high risk of death from heart disease [NIH ODS]. Calcium can also reduce the absorption of medications including bisphosphonates, tetracycline antibiotics, fluoroquinolone antibiotics, levothyroxine, and phenytoin [NIH ODS].
Our recommendation
Before you supplement, assess your dietary intake. For most adults, the data does not support routine high-dose calcium supplementation. If you do take a supplement, take it with food and separate it from your thyroid medication or antibiotics by at least two hours [NIH ODS]. Do not exceed the tolerable upper intake level without your doctor's guidance.
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | Nature Made |
|---|---|
| Serving Size | |
| Contents | 75.0 Tablet(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide