up&up Vitamin E 400 IU
Brand: up&up · Form: SOFTGEL CAPSULE [E0161] On Market
Our assessment
Our assessment: Vitamin E is a fat-soluble antioxidant that helps protect your cells from damage. For most adults, the recommended dietary allowance (RDA) is 15 mg (22.4 IU) daily, and a 400 IU supplement is significantly higher than this target [NIH ODS]. While supplementation can be beneficial for specific deficiencies, the evidence does not support routine high-dose use for the general population.
How it works
Vitamin E works primarily as a chain-breaking antioxidant, which means it stops the spread of free radical reactions in your cell membranes. This protective action helps maintain the integrity of your cells and supports immune function by shielding white blood cells from oxidative damage [NIH ODS].
Safety profile
Data not available for adverse event reports from the FDA data provided. However, high doses of vitamin E (above 1,000 mg daily) can increase the risk of bleeding, particularly for people taking blood-thinning medications like warfarin [NIH ODS]. Because 400 IU (about 268 mg) is well below that threshold, it is generally considered safe for most adults, but you should always consult your healthcare provider before starting any new supplement.
Our recommendation
For most people, getting vitamin E from food sources—such as nuts, seeds, and vegetable oils—is the best approach. If you are considering a 400 IU supplement, discuss it with your pharmacist or doctor to ensure it is appropriate for your specific health needs and does not interact with any medications you take [NIH ODS].
AI-assisted analysis. Data sourced from NIH DSLD.
Supplement Facts
| Brand | up&up |
|---|---|
| Serving Size | |
| Contents | 250.0 Softgel(s) |
| Market Status | On Market |
How to Read This Label
Supplement labels contain several key sections regulated by the FDA:
- Serving Size — The recommended amount per dose. Always check this — some products require multiple capsules per serving.
- Amount Per Serving — Shows the quantity of each nutrient in the product, typically in IU (International Units), mg (milligrams), or mcg (micrograms).
- % Daily Value (%DV) — Indicates how much a nutrient in a serving contributes to a daily diet. 5% DV or less is low; 20% DV or more is high.
- Other Ingredients — Lists inactive ingredients like fillers, binders, and capsule materials (e.g., gelatin, cellulose, magnesium stearate).
- Suggested Use — The manufacturer's recommended directions for taking the supplement, including timing and dosage.
Source: FDA Dietary Supplement Labeling Guide